Treating Chronic Fatigue Syndrome - Cucurmin
Cucurmin Is derived from tumeric, a staple of Indian cusine and Aryuvedic medicine
for thousands of years. Known for its aromatic, stimulant and carminative properties
tumeric has been used in traditional
Chinese medicine to treat liver and gallbladder problems and stimulate digestion.
Some physicians have recently begun to use curcumin to treat chronic fatigue
syndrome (ME/CFS) as well.
The biologically active phytochemical present in tumeric, curcumin was first
isolated in 1910. Animal studies suggest it has anti-inflammatory, anti-viral,
anti-tumor, antioxidant and anti-ischemic properties - all of which may be of
concern in CFS. Cucurmins ability to reduce neuroinflammation and oxidative
stress in the brain may be of particular interest to ME/CFS patients.
Studies suggest curcumin may be able to assist with exercise, learning,
overstimulation and depression. Cucurmin's anti-inflammatory properties have
been used to reduce the swelling and arthritis and ease muscle pains from
exercise. Studies suggest it may be helpful in many inflammatory conditions
including diabetes, arthritis, aetherosclerosis and inflammatory bowel as well
as fibromyalgia and peripheral neuropathy.
Curcumin may have similar effects as anti-Tumor Necrosis Factor (TNF)
drugs, some of which are being explored in special subsets of CFS patients and
as anti-NF-kB drugs. Some researchers believe that NF-kB, a
transcription factor that promotes inflammatory conditions, is overactive in
chronic fatigue syndrome (ME/CFS). Cucurmin also appears to have positive
effects on amyloid production in rodent studies on Alzheimer's - an intriguing
finding given that one study suggests amyloid deposition may be occurring in the
ME/CFS patients as well. Curcumin is also a potent nitric oxide free radical
scavenger and can reduce F2 isoprostane levels - which studies indicate
are high in CFS.
A Patent Court's ruling that tumeric's properties were not patentable may have
blunted pharmaceutical companies interest but clinical trials are under way in a
wide variety of diseases including several cancers, psoriasis and Alzheimer's
disease. Interestingly, a recent study found that cucurmin was more effective
than a refined metabolite of cucurmin called Tetrohydrocurcumin. The study
established that curcumin supplementation is the most effective means of
receiving this treatments benefits.
Some studies have questioned whether cucurmin absorption is sufficient for its
effects to take place. A 2006 study found that even 'high dosing levels' did not
result in detectable levels of curcumin in the plasma. A 2008 study suggested,
however, that supplementing curcurmin with olive oil, phosphatidyl choline or
stearic acid increases curcurmin plasma levels 11-fold and brain levels 4-fold.
Curcumin absorption may be increased when it is not taken with other food. The
studies authors suggested that traditional Indian culinary practices of
dissolving tumeric in fat while cooking could contribute to reduced levels of
Alzheimers in India.
Cucurmin Might Be Helpful In Chronic Fatigue Syndrome (ME/CFS)
Because because it's anti-inflammatory and anti-oxidant properties may help combat the
inflammation present in some patients.
Chronic Fatigue Syndrome (ME/CFS) Studies - None
Chronic Fatigue Syndrome (ME/CFS) Doctor's Report - None
Chronic Fatigue Syndrome (ME/CFS) Patients Report - None
Recommended Dose: 500-1,000 mgs/day - can be increased
due to low incidence of side effects
Side Effects: none reported
Resources:
A Golden Gift of Nature
http://www.herbalextractsplus.com/curcumin.cfm
Tumeric-cucurmin.com